Oral versus high-dose pulse corticosteroids for problematic infantile hemangiomas: a randomized, controlled trial

E Pope, BR Krafchik, C Macarthur, D Stempak… - …, 2007 - publications.aap.org
OBJECTIVES. Oral systemic corticosteroids are the mainstay of treatment for problematic
hemangiomas; however, current information is based on anecdotal experience and
retrospective studies. We aimed to determine whether systemic steroids are efficacious in
proliferating hemangioma and to compare the efficacy and safety of 2 corticosteroid
treatment modalities. PATIENTS AND METHODS. Twenty patients with problematic
hemangiomas of infancy were randomly assigned to either daily oral prednisolone or …