Response to Roberts et al. 2018: cohort ascertainment and methods of analysis impact the association between cancer and genetic predisposition-the tale of breast …
X Wang, JP Brzosowicz, JY Park - Genetics in Medicine, 2019 - nature.com
X Wang, JP Brzosowicz, JY Park
Genetics in Medicine, 2019•nature.com1. Roberts ME, Jackson SA, Susswein LR, et al. MSH6 and PMS2 germ-line pathogenic
variants implicated in Lynch syndrome are associated with breast cancer. Genet Med. 2018;
20: 1167–1174. 2. Couch FJ, Shimelis H, Hu C, et al. Associations between cancer
predisposition testing panel genes and breast cancer. JAMA Oncol. 2017; 3: 1190–1196. 3.
ten Broeke SW, Suerink M, Nielsen M. Response to Roberts et al. 2018: is breast cancer
truly caused by MSH6 and PMS2 variants or is it simply due to a high prevalence of these …
variants implicated in Lynch syndrome are associated with breast cancer. Genet Med. 2018;
20: 1167–1174. 2. Couch FJ, Shimelis H, Hu C, et al. Associations between cancer
predisposition testing panel genes and breast cancer. JAMA Oncol. 2017; 3: 1190–1196. 3.
ten Broeke SW, Suerink M, Nielsen M. Response to Roberts et al. 2018: is breast cancer
truly caused by MSH6 and PMS2 variants or is it simply due to a high prevalence of these …
1. Roberts ME, Jackson SA, Susswein LR, et al. MSH6 and PMS2 germ-line pathogenic variants implicated in Lynch syndrome are associated with breast cancer. Genet Med. 2018; 20: 1167–1174. 2. Couch FJ, Shimelis H, Hu C, et al. Associations between cancer predisposition testing panel genes and breast cancer. JAMA Oncol. 2017; 3: 1190–1196.
3. ten Broeke SW, Suerink M, Nielsen M. Response to Roberts et al. 2018: is breast cancer truly caused by MSH6 and PMS2 variants or is it simply due to a high prevalence of these variants in the population? Genet Med. 2019; 21: 256–257.
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