[CITATION][C] Levels of the TNF related cytokine, LIGHT increase in hospitalized COVID-19 patients with Cytokine Release Syndrome and ARDS (preprint)
DS Perlin, I Zafir-Lavie, L Roadcap, S Raines, CF Ware… - 2020
[PDF][PDF] Levels of the TNF-related cytokine LIGHT increase in hospitalized COVID-19 patients with cytokine release syndrome and ARDS. mSphere. 5: e00699-20
DS Perlin, I Zafir-Lavie, L Roadcap, S Raines, CF Ware… - 2020 - academia.edu
ABSTRACT Many coronavirus disease 2019 (COVID-19) patients demonstrate lethal
respiratory complications caused by cytokine release syndrome (CRS). Multiple cytokines
have been implicated in CRS, but levels of tumor necrosis factor superfamily 14
(TNFSF14)(LIGHT) have not been previously measured in this setting. In this study, we
observed significantly elevated serum LIGHT levels in hospitalized COVID-19 patients
compared to healthy age-and gender-matched control patients. The assay detected …
respiratory complications caused by cytokine release syndrome (CRS). Multiple cytokines
have been implicated in CRS, but levels of tumor necrosis factor superfamily 14
(TNFSF14)(LIGHT) have not been previously measured in this setting. In this study, we
observed significantly elevated serum LIGHT levels in hospitalized COVID-19 patients
compared to healthy age-and gender-matched control patients. The assay detected …
