Protective effect of low potassium dextran solution on acute kidney injury following acute lung injury induced by oleic acid in piglets

RP Wu, X Liang, G Hui, X Zhou, Z Li… - Chinese medical …, 2012 - journals.lww.com
Background Low potassium dextran (LPD) solution can attenuate acute lung injury (ALI).
However, LPD solution for treating acute kidney injury secondary to ALI has not been
reported. The present study was performed to examine the renoprotective effect of LPD
solution in ALI induced by oleic acid (OA) in piglets. Methods Twelve animals that suffered
an ALI induced by administration of OA into the right atrium were divided into two groups: the
placebo group (n= 6) pretreated with normal saline and the LPD group (n= 6), pretreated …