oPOSSUM-3: advanced analysis of regulatory motif over-representation across genes or ChIP-Seq datasets
AT Kwon, DJ Arenillas, RW Hunt… - G3: Genes| Genomes …, 2012 - academic.oup.com
G3: Genes| Genomes| Genetics, 2012•academic.oup.com
Abstract oPOSSUM-3 is a web-accessible software system for identification of over-
represented transcription factor binding sites (TFBS) and TFBS families in either DNA
sequences of co-expressed genes or sequences generated from high-throughput methods,
such as ChIP-Seq. Validation of the system with known sets of co-regulated genes and
published ChIP-Seq data demonstrates the capacity for oPOSSUM-3 to identify mediating
transcription factors (TF) for co-regulated genes or co-recovered sequences. oPOSSUM-3 is …
represented transcription factor binding sites (TFBS) and TFBS families in either DNA
sequences of co-expressed genes or sequences generated from high-throughput methods,
such as ChIP-Seq. Validation of the system with known sets of co-regulated genes and
published ChIP-Seq data demonstrates the capacity for oPOSSUM-3 to identify mediating
transcription factors (TF) for co-regulated genes or co-recovered sequences. oPOSSUM-3 is …
Abstract
oPOSSUM-3 is a web-accessible software system for identification of over-represented transcription factor binding sites (TFBS) and TFBS families in either DNA sequences of co-expressed genes or sequences generated from high-throughput methods, such as ChIP-Seq. Validation of the system with known sets of co-regulated genes and published ChIP-Seq data demonstrates the capacity for oPOSSUM-3 to identify mediating transcription factors (TF) for co-regulated genes or co-recovered sequences. oPOSSUM-3 is available at http://opossum.cisreg.ca.
Oxford University Press