[HTML][HTML] Molecular and functional characterization of the endothelial ATP-sensitive potassium channel

Q Aziz, Y Li, N Anderson, L Ojake, E Tsisanova… - Journal of Biological …, 2017 - ASBMB
ATP-sensitive potassium (K ATP) channels are widely expressed in the cardiovascular
system, where they regulate a range of biological activities by linking cellular metabolism
with membrane excitability. K ATP channels in vascular smooth muscle have a well-defined
role in regulating vascular tone. K ATP channels are also thought to be expressed in
vascular endothelial cells, but their presence and function in this context are less clear. As a
result, we aimed to investigate the molecular composition and physiological role of …