A comparison of positive family history definitions for defining risk of future disease
SC Hunt, RR Williams, GK Barlow - Journal of chronic diseases, 1986 - Elsevier
The relative risk of developing future coronary heart disease (CHD) or hypertension
between positive and negative family history families is compared for different definitions of
a positive family history when applied to life-table data for 94,292 persons. Having two or
more first degree relatives with CHD identifies 8% of the population with relative risks of 3.3–
5.9 for CHD before age 50. A quantitative family history score (FHS) compares the family's
age and sex specific disease incidence to that expected in the general population and …
between positive and negative family history families is compared for different definitions of
a positive family history when applied to life-table data for 94,292 persons. Having two or
more first degree relatives with CHD identifies 8% of the population with relative risks of 3.3–
5.9 for CHD before age 50. A quantitative family history score (FHS) compares the family's
age and sex specific disease incidence to that expected in the general population and …