The receptor-mediated uptake, survival, replication, and drug sensitivity of Mycobacterium tuberculosis within the macrophage-like cell line THP-1: a comparison with …
RW Stokes, D Doxsee - Cellular immunology, 1999 - Elsevier
We have compared the interaction of Mycobacterium tuberculosis with the human
macrophage-like cell line THP-1 and with human monocyte-derived macrophages (MDM).
The association of M. tuberculosis with THP-1 and MDM was comparable in both the
presence and the absence of serum. For both cells, serum-mediated binding was much
greater than nonopsonic binding and was mediated by a heat-labile serum component.
Nonopsonic binding of M. tuberculosis to both cells could be inhibited by antibodies …
macrophage-like cell line THP-1 and with human monocyte-derived macrophages (MDM).
The association of M. tuberculosis with THP-1 and MDM was comparable in both the
presence and the absence of serum. For both cells, serum-mediated binding was much
greater than nonopsonic binding and was mediated by a heat-labile serum component.
Nonopsonic binding of M. tuberculosis to both cells could be inhibited by antibodies …