Kinetics of viral load and cytokines in severe fever with thrombocytopenia syndrome
JS Kwon, MC Kim, JY Kim, NY Jeon, BH Ryu… - Journal of Clinical …, 2018 - Elsevier
Background Severe fever with thrombocytopenia syndrome (SFTS) is an emerging
infectious disease in China, Japan, and Korea, which is characterized by high fever,
thrombocytopenia, and high mortality. It is hypothesized that a cytokine storm plays an
important role in the pathophysiology of SFTS. However, limited data have been published
on the detailed kinetics of the viral load and cytokine profiles throughout the course of this
disease. Objectives We investigated the patterns of changes in cytokines and viral load in …
infectious disease in China, Japan, and Korea, which is characterized by high fever,
thrombocytopenia, and high mortality. It is hypothesized that a cytokine storm plays an
important role in the pathophysiology of SFTS. However, limited data have been published
on the detailed kinetics of the viral load and cytokine profiles throughout the course of this
disease. Objectives We investigated the patterns of changes in cytokines and viral load in …