[HTML][HTML] Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding …

R Bartenschlager, TF Baumert, J Bukh, M Houghton… - Virus research, 2018 - Elsevier
The development and clinical implementation of direct-acting antivirals (DAAs) has
revolutionized the treatment of chronic hepatitis C. Infection with any hepatitis C virus (HCV)
genotype can now be eliminated in more than 95% of patients with short courses of all-oral,
well-tolerated drugs, even in those with advanced liver disease and liver transplant
recipients. DAAs have proven so successful that some now consider HCV amenable to
eradication, and continued research on the virus of little remaining medical relevance …