DNA methylation is a focus of epigenetic research in the immune system. This overview
begins with a synopsis of the players and processes involved in DNA methylation,
demethylation, methyl-CpG-recognition, histone modification, and chromatin remodeling.
The role of these mechanisms in immune responses, with a focus on T lymphocytes, is then
reviewed. There is evidence for epigenetic regulation of several key immune processes
including thymocyte development, antigen presentation, differentiation, cytokine expression …