Importance Recent advances in stem cell technologies have rekindled an interest in the use
of cell replacement strategies for patients with Parkinson disease. This study reports the very
long-term clinical outcomes of fetal cell transplantation in 2 patients with Parkinson disease.
Such long-term follow-up data can usefully inform on the potential efficacy of this approach,
as well as the design of trials for its further evaluation. Observations Two patients received
intrastriatal grafts of human fetal ventral mesencephalic tissue, rich in dopaminergic …