Context In addition to trauma exposure, other factors contribute to risk for development of
posttraumatic stress disorder (PTSD) in adulthood. Both genetic and environmental factors
are contributory, with child abuse providing significant risk liability. Objective To increase
understanding of genetic and environmental risk factors as well as their interaction in the
development of PTSD by gene× environment interactions of child abuse, level of non–child
abuse trauma exposure, and genetic polymorphisms at the stress-related gene FKBP5 …