Pyseer: a comprehensive tool for microbial pangenome-wide association studies

JA Lees, M Galardini, SD Bentley, JN Weiser… - …, 2018 - academic.oup.com
Bioinformatics, 2018academic.oup.com
Genome-wide association studies (GWAS) in microbes have different challenges to GWAS
in eukaryotes. These have been addressed by a number of different methods. pyseer brings
these techniques together in one package tailored to microbial GWAS, allows greater
flexibility of the input data used, and adds new methods to interpret the association results.
Availability and implementation pyseer is written in python and is freely available at
https://github. com/mgalardini/pyseer, or can be installed through pip. Documentation and a …
Summary
Genome-wide association studies (GWAS) in microbes have different challenges to GWAS in eukaryotes. These have been addressed by a number of different methods. pyseer brings these techniques together in one package tailored to microbial GWAS, allows greater flexibility of the input data used, and adds new methods to interpret the association results.
Availability and implementation
pyseer is written in python and is freely available at https://github.com/mgalardini/pyseer, or can be installed through pip. Documentation and a tutorial are available at http://pyseer.readthedocs.io.
Supplementary information
Supplementary data are available at Bioinformatics online.
Oxford University Press