[HTML][HTML] Functional interactions of mitochondrial DNA polymerase and single-stranded DNA-binding protein: template-primer DNA binding and initiation and …

CL Farr, Y Wang, LS Kaguni - Journal of biological chemistry, 1999 - ASBMB
Functional interactions between mitochondrial DNA polymerase (pol γ) and mitochondrial
single-stranded DNA-binding protein (mtSSB) from Drosophila embryos have been
evaluated with regard to the overall activity of pol γ and in partial reactions involving
template-primer binding and initiation and idling in DNA strand synthesis. Both the 5′→ 3′
DNA polymerase and 3′→ 5′ exonuclease in pol γ are stimulated 15–20-fold on
oligonucleotide-primed single-stranded DNA by native and recombinant forms of mtSSB …