[HTML][HTML] Human immune memory to yellow fever and smallpox vaccination

J Wrammert, J Miller, R Akondy, R Ahmed - Journal of clinical immunology, 2009 - Springer
Journal of clinical immunology, 2009Springer
Background Establishment of immunological memory is a hallmark of adaptive immune
responses and the biological mechanism for the success of vaccines. However, in humans,
much of our knowledge about adaptive immune responses derives from studies of chronic
viral infections. Objective Here, we summarize the work of our laboratory and others on B
and T cell responses and the establishment and maintenance of immune memory after
acute viral infections induced by vaccination with two of the most successful vaccines to …
Background
Establishment of immunological memory is a hallmark of adaptive immune responses and the biological mechanism for the success of vaccines. However, in humans, much of our knowledge about adaptive immune responses derives from studies of chronic viral infections.
Objective
Here, we summarize the work of our laboratory and others on B and T cell responses and the establishment and maintenance of immune memory after acute viral infections induced by vaccination with two of the most successful vaccines to date, the yellow fever and the smallpox vaccines.
Springer