Renoprotection of Optimal Antiproteinuric Doses (ROAD) Study: a randomized controlled study of benazepril and losartan in chronic renal insufficiency
FF Hou, D Xie, X Zhang, PY Chen… - Journal of the …, 2007 - journals.lww.com
Abstract The Renoprotection of Optimal Antiproteinuric Doses (ROAD) study was performed
to determine whether titration of benazepril or losartan to optimal antiproteinuric doses
would safely improve the renal outcome in chronic renal insufficiency. A total of 360 patients
who did not have diabetes and had proteinuria and chronic renal insufficiency were
randomly assigned to four groups. Patients received open-label treatment with a
conventional dosage of benazepril (10 mg/d), individual uptitration of benazepril (median 20 …
to determine whether titration of benazepril or losartan to optimal antiproteinuric doses
would safely improve the renal outcome in chronic renal insufficiency. A total of 360 patients
who did not have diabetes and had proteinuria and chronic renal insufficiency were
randomly assigned to four groups. Patients received open-label treatment with a
conventional dosage of benazepril (10 mg/d), individual uptitration of benazepril (median 20 …
