Chronic pancreatitis changes in high-risk individuals for pancreatic ductal adenocarcinoma

SS Thiruvengadam, J Chuang, R Huang… - Gastrointestinal …, 2019 - Elsevier
Background and Aims Pancreatic intraepithelial neoplasia is associated with chronic
pancreatitis (CP) changes on EUS. The objective of this study was to determine whether CP
changes were more common in high-risk individuals (HRIs) than in control subjects and
whether these changes differed among higher-risk subsets of HRIs. Methods HRIs and
control subjects were identified from an endoscopy database. HRIs were defined as having
predisposing mutations or a family history (FH) of pancreatic ductal adenocarcinoma. HRIs …