Comparative analysis of immunocritical melanoma markers in the mouse melanoma cell lines B16, K1735 and S91-M3
I Peter, A Mezzacasa, P LeDonne, R Dummer… - Melanoma …, 2001 - journals.lww.com
The mouse melanoma cell lines B16, K1735 and Cloudman S91-M3 (and various sublines)
are frequently used as melanoma models. Extensive comparative data of their
immunological features are not available. In order to define the immunological profiles of
these cell lines, relevant tumour markers were studied. S91-M3 melanoma cells
constitutively expressed high levels of major histocompatibility complex (MHC) I, in contrast
to K1735-M2 and B16-F1 cells. MHC II expression was restricted to B16-F1 cells following …
are frequently used as melanoma models. Extensive comparative data of their
immunological features are not available. In order to define the immunological profiles of
these cell lines, relevant tumour markers were studied. S91-M3 melanoma cells
constitutively expressed high levels of major histocompatibility complex (MHC) I, in contrast
to K1735-M2 and B16-F1 cells. MHC II expression was restricted to B16-F1 cells following …