Elevated plasma levels of ED1+ (“cellular”) fibronectin in patients with vascular injury
JH Peters, RJ Maunder, AD Woolf… - The Journal of …, 1989 - translationalres.com
Using an enzyme-linked immunosorbent assay, we measured the concentration of
fibronectin containing an extra type III domain (ED1) in the circulation of humans. Plasma
levels of ED1+ fibronectin averaged 2.8±1.0 μg/ml in healthy individuals and did not differ
substantially according to age or sex. In comparison with those from normal subjects,
plasma samples obtained from patients with collagen vascular disorders contained
increased average levels of ED1+ fibronectin. Among this group, levels of ED1+ fibronectin …
fibronectin containing an extra type III domain (ED1) in the circulation of humans. Plasma
levels of ED1+ fibronectin averaged 2.8±1.0 μg/ml in healthy individuals and did not differ
substantially according to age or sex. In comparison with those from normal subjects,
plasma samples obtained from patients with collagen vascular disorders contained
increased average levels of ED1+ fibronectin. Among this group, levels of ED1+ fibronectin …