Aberrant G-protein coupled hormone receptor in adrenal diseases
M St-Jean, N El Ghorayeb, I Bourdeau… - Best Practice & Research …, 2018 - Elsevier
The regulation of cortisol or aldosterone production when ACTH of pituitary origin or the
renin-angiotensin systems are suppressed in primary adrenal Cushing's syndrome or in
primary aldosteronism is exerted by diverse genetic and molecular mechanisms. In addition
to recently identified mutations in various genes implicated in the cyclic AMP or ion channel
pathways, steroidogenesis is not really autonomous as it is frequently regulated by the
aberrant adrenocortical expression of diverse hormone receptors, particularly G-protein …
renin-angiotensin systems are suppressed in primary adrenal Cushing's syndrome or in
primary aldosteronism is exerted by diverse genetic and molecular mechanisms. In addition
to recently identified mutations in various genes implicated in the cyclic AMP or ion channel
pathways, steroidogenesis is not really autonomous as it is frequently regulated by the
aberrant adrenocortical expression of diverse hormone receptors, particularly G-protein …
