Iron deficiency and brain development

B Lozoff, MK Georgieff - Seminars in pediatric neurology, 2006 - Elsevier
Iron deficiency (ID) is common in pregnant women and infants worldwide. Rodent models
show that ID during gestation/lactation alters neurometabolism, neurotransmitters,
myelination, and gene/protein profiles before and after iron repletion at weaning. Human
infants with iron deficiency anemia test lower in cognitive, motor, social-emotional, and
neurophysiologic development than comparison group infants. Iron therapy does not
consistently improve developmental outcome, with long-term differences observed. Poorer …