UTP as an extracellular signaling molecule
ER Lazarowski, RC Boucher - Physiology, 2001 - journals.physiology.org
ER Lazarowski, RC Boucher
Physiology, 2001•journals.physiology.orgIn addition to their central role in many biochemical processes, uridine nucleotides are
important extracellular signaling molecules that regulate a broad spectrum of cell functions
via activation of P2Y2, P2Y4, and P2Y6 receptors. Cellular release of UTP provides a
mechanism for autocrine control of calcium-or protein kinase C–dependent processes.
important extracellular signaling molecules that regulate a broad spectrum of cell functions
via activation of P2Y2, P2Y4, and P2Y6 receptors. Cellular release of UTP provides a
mechanism for autocrine control of calcium-or protein kinase C–dependent processes.
In addition to their central role in many biochemical processes, uridine nucleotides are important extracellular signaling molecules that regulate a broad spectrum of cell functions via activation of P2Y2, P2Y4, and P2Y6 receptors. Cellular release of UTP provides a mechanism for autocrine control of calcium- or protein kinase C–dependent processes.
American Physiological Society