Venous thrombosis, including deep vein thrombosis (DVT) and pulmonary embolism (PE),
occurs at an annual incidence of about 1 per 1,000 adults. Rates increase sharply after
about age 45 years, and are slightly higher in men than women in older age. Major risk
factors for thrombosis, other than age, include exogenous factors such as surgery,
hospitalization, immobility, trauma, pregnancy, and the puerperium and hormone use, and
endogenous factors such as cancer, obesity, and inherited and acquired disorders of …