Bone invasion by oral squamous cell carcinoma: molecular alterations leading to osteoclastogenesis–a review of literature
LAA Vaassen, EJM Speel, PAWH Kessler - Journal of Cranio-Maxillofacial …, 2017 - Elsevier
Oral squamous cell carcinoma (OSCC) is a growing problem globally. OSCC often arises in
close anatomical relation to the jaws and may invade the bone. Bone invasion by OSCC has
major implications on tumor staging, choice of treatment, outcome, and quality of life. The
difference in cortical or medullary bone invasion has implications for these factors.
Treatment protocols used for cortical and medullary invasion differ worldwide. By
researching possible pathways a more molecular-based clinical staging and tailor-made …
close anatomical relation to the jaws and may invade the bone. Bone invasion by OSCC has
major implications on tumor staging, choice of treatment, outcome, and quality of life. The
difference in cortical or medullary bone invasion has implications for these factors.
Treatment protocols used for cortical and medullary invasion differ worldwide. By
researching possible pathways a more molecular-based clinical staging and tailor-made …