D-lactic acidosis in a man with the short-bowel syndrome

MS Oh, KR Phelps, M Traube… - … England Journal of …, 1979 - Mass Medical Soc
MS Oh, KR Phelps, M Traube, JL Barbosa-Saldivar, C Boxhill, HJ Carroll
New England Journal of Medicine, 1979Mass Medical Soc
WE have recently studied a patient who had short-bowel syndrome that presented with
peculiar neurologic manifestations and severe metabolic acidosis. The anion gap was
increased, but the identity of the abnormal anion was not readily apparent. By several
chemical technics the agent responsible for metabolic acidosis was found to be D-lactic acid—
a cause of metabolic acidosis familiar to veterinarians but not to physicians. Case History
The patient, a 30-year-old man, was in good health until July, 1975, when a superior …
WE have recently studied a patient who had short-bowel syndrome that presented with peculiar neurologic manifestations and severe metabolic acidosis. The anion gap was increased, but the identity of the abnormal anion was not readily apparent. By several chemical technics the agent responsible for metabolic acidosis was found to be D-lactic acid — a cause of metabolic acidosis familiar to veterinarians but not to physicians.
Case History
The patient, a 30-year-old man, was in good health until July, 1975, when a superior mesenteric-vein thrombosis of unknown cause resulted in gangrene of most of the small intestine. After emergency jejunoileostomy with . . .
The New England Journal Of Medicine