[HTML][HTML] The tetraspan protein EMP2 regulates expression of caveolin-1
A Forbes, M Wadehra, S Mareninov, S Morales… - Journal of Biological …, 2007 - ASBMB
Caveolin-1 is the primary component of caveolae and functions in a variety of intracellular
activities, including membrane trafficking and signal transduction. EMP2 (epithelial
membrane protein 2) is a tetraspan protein recently identified as a novel regulator of
caveolin-1 expression. In this study, we analyzed the mechanism of EMP2-mediated
caveolin-1 regulation. In NIH 3T3 cells and in the human retinal pigment epithelium cell line
(ARPE-19), EMP2 regulates caveolin-1 transcription and more substantially its protein …
activities, including membrane trafficking and signal transduction. EMP2 (epithelial
membrane protein 2) is a tetraspan protein recently identified as a novel regulator of
caveolin-1 expression. In this study, we analyzed the mechanism of EMP2-mediated
caveolin-1 regulation. In NIH 3T3 cells and in the human retinal pigment epithelium cell line
(ARPE-19), EMP2 regulates caveolin-1 transcription and more substantially its protein …