[HTML][HTML] Cloning of the mouse class IV alcohol dehydrogenase (retinol dehydrogenase) cDNA and tissue-specific expression patterns of the murine ADH gene family

M Žgombić-Knight, HL Ang, MH Foglio… - Journal of Biological …, 1995 - ASBMB
Humans possess five classes of alcohol dehydrogenase (ADH), including forms able to
oxidize ethanol or formaldehyde as part of a defense mechanism, as well as forms acting as
retinol dehydrogenases in the synthesis of the regulatory ligand retinoic acid. However, the
mouse has previously been shown to possess only three forms of ADH. Hybridization
analysis of mouse genomic DNA using cDNA probes specific for each of the five classes of
human ADH has now indicated that mouse DNA cross-hybridizes to only classes I, III, and …