Rac, a novel ras-related family of proteins that are botulinum toxin substrates
J Didsbury, RF Weber, GM Bokoch, T Evans… - Journal of Biological …, 1989 - ASBMB
A new family of ras-related proteins, designated rac (ras-related C3 botulinum toxin
substrate) has been identified. rac1 and rac2 cDNA clones were isolated from a
differentiated HL-60 library and encode proteins that are 92% homologous and share 58%
and 26-30% amino acid homology with human rhos and ras, respectively. Nucleotide
sequence analysis predicts both rac1 and rac2 proteins to contain 192 amino acids with
molecular masses of 21,450 and 21,429 daltons, respectively. rac1 and rac2 possess four of …
substrate) has been identified. rac1 and rac2 cDNA clones were isolated from a
differentiated HL-60 library and encode proteins that are 92% homologous and share 58%
and 26-30% amino acid homology with human rhos and ras, respectively. Nucleotide
sequence analysis predicts both rac1 and rac2 proteins to contain 192 amino acids with
molecular masses of 21,450 and 21,429 daltons, respectively. rac1 and rac2 possess four of …