Impact of angiotensin-converting enzyme inhibitors and statins on survival in idiopathic pulmonary fibrosis
HF Nadrous, JH Ryu, WW Douglas, PA Decker… - Chest, 2004 - Elsevier
Study objectives: To assess the clinical relevance of angiotensin-converting enzyme
inhibitors (ACEI) and 3-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitors (statins)
in the context of idiopathic pulmonary fibrosis (IPF). Background: IPF is a progressive
interstitial lung disease for which there is no effective treatment. ACEI and statins have been
shown to possess antifibrotic properties in experimental models in vitro and in vivo. Design,
setting, and patients: Retrospective review of the effects of ACEI and statins on survival of …
inhibitors (ACEI) and 3-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitors (statins)
in the context of idiopathic pulmonary fibrosis (IPF). Background: IPF is a progressive
interstitial lung disease for which there is no effective treatment. ACEI and statins have been
shown to possess antifibrotic properties in experimental models in vitro and in vivo. Design,
setting, and patients: Retrospective review of the effects of ACEI and statins on survival of …