[HTML][HTML] Monitoring of human cytomegalovirus-specific CD4+ and CD8+ T-cell immunity in patients receiving solid organ transplantation

G Gerna, D Lilleri, C Fornara, G Comolli, L Lozza… - American Journal of …, 2006 - Elsevier
Absolute and human cytomegalovirus (HCMV)-specific CD4+ and CD8+ T-cell counts were
monitored in 38 solid organ (20 heart, 9 lung and 9 kidney) transplant recipients during the
first year after transplantation by a novel assay based on T-cell stimulation with HCMV-
infected autologous dendritic cells. According to the pattern of T-cell restoration occurring
either within the first month after transplantation or later, patients were classified as either
early (n= 21) or late responders (n= 17). HCMV-specific CD4+ and CD8+ T-cell counts were …