Endosomal toll-like receptor gene polymorphisms and susceptibility to HIV and HCV co-infection–Differential influence in individuals with distinct ethnic background
JM Valverde-Villegas, BP Dos Santos… - Human Immunology, 2017 - Elsevier
The genetic background of human populations can influence the susceptibility and outcome
of infection diseases. Toll-like receptors (TLRs) have been previously associated with
susceptibility to human immunodeficiency virus (HIV) infection, disease progression and
hepatitis C, virus (HCV) co-infection in different populations, although mostly in Europeans.
In this study, we investigated the genetic role of endosomal TLRs on susceptibility to HIV
infection and HCV co-infection through the analysis of TLR7 rs179008, TLR8 rs3764880 …
of infection diseases. Toll-like receptors (TLRs) have been previously associated with
susceptibility to human immunodeficiency virus (HIV) infection, disease progression and
hepatitis C, virus (HCV) co-infection in different populations, although mostly in Europeans.
In this study, we investigated the genetic role of endosomal TLRs on susceptibility to HIV
infection and HCV co-infection through the analysis of TLR7 rs179008, TLR8 rs3764880 …