The Neuropilins (Nrps) are a family of essential cell surface receptors involved in multiple
fundamental cellular signaling cascades. Nrp family members have key functions in VEGF-
dependent angiogenesis and semaphorin-dependent axon guidance, controlling signaling
and cross-talk between these fundamental physiological processes. More recently, Nrp
function has been found in diverse signaling and adhesive functions, emphasizing their role
as pleiotropic co-receptors. Pathological Nrp function has been shown to be important in …