Multicenter approach to recurrent acute and chronic pancreatitis in the United States: the North American Pancreatitis Study 2 (NAPS2)
DC Whitcomb, D Yadav, S Adam, RH Hawes… - Pancreatology, 2008 - Elsevier
Background: Recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP) are complex
syndromes associated with numerous etiologies, clinical variables and complications. We
developed the North American Pancreatitis Study 2 (NAPS2) to be sufficiently powered to
understand the complex environmental, metabolic and genetic mechanisms underlying RAP
and CP. Methods: Between August 2000 and September 2006, a consortium of 20 expert
academic and private sites prospectively ascertained 1,000 human subjects with RAP or CP …
syndromes associated with numerous etiologies, clinical variables and complications. We
developed the North American Pancreatitis Study 2 (NAPS2) to be sufficiently powered to
understand the complex environmental, metabolic and genetic mechanisms underlying RAP
and CP. Methods: Between August 2000 and September 2006, a consortium of 20 expert
academic and private sites prospectively ascertained 1,000 human subjects with RAP or CP …