The Environmental Polymorphism Registry: a unique resource that facilitates translational research of environmental disease

PC Chulada, E Vainorius, S Garantziotis… - Environmental …, 2011 - ehp.niehs.nih.gov
Background: Dissecting complex disease has become more feasible because of the
availability of large-scale DNA resources and advances in high-throughput genomic
technology. Although these tools help scientists identify potential susceptibility loci, subjects
with relevant genotypes are needed for clinical phenotyping and toxicity studies. Objective:
We have developed a resource of subjects and their DNA to use for translational research of
environmental disease. Methods: More than 15,000 individuals of diverse sex, age, race …