Lipid droplets are evolutionarily conserved organelles where cellular fat storage and
mobilization are exquisitely regulated. Recent studies have defined lipid droplets in C.
elegans and explored how they are regulated by genetic and dietary factors. C. elegans
offers unique opportunities to visualize lipid droplets at single-cell resolution in live animals.
The development of novel microscopy techniques and protein markers for lipid droplets will
accelerate studies on how nutritional states and subcellular organization are linked in vivo …