Perilipin is located on the surface layer of intracellular lipid droplets in adipocytes.

EJ Blanchette-Mackie, NK Dwyer, T Barber… - Journal of lipid …, 1995 - ASBMB
Immunocytochemistry was used to determine the intracellular location of perilipins in
adipocytes and the occurrence of these proteins in tissues involved in triacylglycerol
metabolism. Confocal microscopy and 3-dimensional analysis of 3T3-L1 adipocytes showed
that perilipin immunofluorescence, present on the surfaces of all sized lipid droplets,
appeared unevenly dispersed on the surfaces of many large lipid droplets. Electron
microscopy revealed that immunogold staining for perilipin was located directly on the …