Decreased fibrosis during corticosteroid therapy of autoimmune hepatitis
AJ Czaja, HA Carpenter - Journal of hepatology, 2004 - Elsevier
BACKGROUND/AIMS: Reduction in hepatic fibrosis and reversibility of cirrhosis has been
described in chronic liver disease. Our goal was to determine changes in fibrosis and the
frequency of histological cirrhosis in corticosteroid-treated autoimmune hepatitis (AIH).
METHODS: Three hundred twenty-five liver specimens from 87 treated patients were
reviewed in batch under code by one pathologist and graded by the Ishak method.
RESULTS: Fibrosis scores improved (3.4±0.2 versus 2.6±0.2, P= 0.0002) during 63±6 …
described in chronic liver disease. Our goal was to determine changes in fibrosis and the
frequency of histological cirrhosis in corticosteroid-treated autoimmune hepatitis (AIH).
METHODS: Three hundred twenty-five liver specimens from 87 treated patients were
reviewed in batch under code by one pathologist and graded by the Ishak method.
RESULTS: Fibrosis scores improved (3.4±0.2 versus 2.6±0.2, P= 0.0002) during 63±6 …