Low-fat dietary pattern and risk of treated diabetes mellitus in postmenopausal women: the Women's Health Initiative randomized controlled dietary modification trial

LF Tinker, DE Bonds, KL Margolis… - Archives of internal …, 2008 - jamanetwork.com
Background Decreased fat intake with weight loss and increased exercise may reduce the
risk of diabetes mellitus in persons with impaired glucose tolerance. This study was
undertaken to assess the effects of a low-fat dietary pattern on incidence of treated diabetes
among generally healthy postmenopausal women. Methods A randomized controlled trial
was conducted at 40 US clinical centers from 1993 to 2005, including 48 835
postmenopausal women aged 50 to 79 years. Women were randomly assigned to a usual …