[HTML][HTML] ApoC-III content of apoB-containing lipoproteins is associated with binding to the vascular proteoglycan biglycan

K Olin-Lewis, RM Krauss, M La Belle, PJ Blanche… - Journal of lipid …, 2002 - ASBMB
Retention of apolipoprotein (apo) B and apoE-containing lipoproteins by extracellular
vascular proteoglycans is critical in atherogenesis. Moreover, high circulating apoC-III levels
are associated with increased atherosclerosis risk. To test whether apoC-III content of apoB-
containing lipoproteins affects their ability to bind to the vascular proteoglycan biglycan, we
evaluated the impact of apoC-III on the interaction of [35 S] SO 4-biglycan derived from
cultured arterial smooth muscle cells with lipoproteins obtained from individuals across a …