Isolation and study of adipocyte precursors
CD Church, R Berry, MS Rodeheffer - Methods in enzymology, 2014 - Elsevier
White adipose tissue (WAT) is a heterogeneous tissue composed of lipid-filled adipocytes
and several nonadipocyte cell populations, including endothelial, blood, uncharacterized
stromal, and adipocyte precursor cells. Although lipid-filled adipocytes account for the
majority of WAT volume and mass, nonadipocyte cell populations have critical roles in WAT
maintenance, growth, and function. As mature adipocytes are terminally differentiated
postmitotic cells, differentiation of adipocyte precursors is required for hyperplastic WAT …
and several nonadipocyte cell populations, including endothelial, blood, uncharacterized
stromal, and adipocyte precursor cells. Although lipid-filled adipocytes account for the
majority of WAT volume and mass, nonadipocyte cell populations have critical roles in WAT
maintenance, growth, and function. As mature adipocytes are terminally differentiated
postmitotic cells, differentiation of adipocyte precursors is required for hyperplastic WAT …