Adipocyte‐specific overexpression of retinol‐binding protein 4 causes hepatic steatosis in mice

SA Lee, JJ Yuen, H Jiang, BB Kahn, WS Blaner - Hepatology, 2016 - journals.lww.com
Increasing evidence supports a role for N‐myc downstream‐regulated gene 2 (NDRG2)
deregulation in tumorigenesis. We investigated the roles and mechanisms of NDRG2 in
human cholangiocarcinoma (CCA) progression. In the present study, expression of NDRG2,
microRNA (miR)‐181c and leukemia inhibitory factor (LIF) in human CCA and adjacent
nontumor tissues were examined. The effects of NDRG2 on CCA tumor growth and
metastasis were determined both in vivo and in vitro. The role of the NDRG2/LIF/miR‐181c …