[HTML][HTML] Regulation of murine cytochrome c oxidase Vb gene expression during myogenesis: YY-1 and heterogeneous nuclear ribonucleoprotein D-like protein …
E Boopathi, N Lenka, SK Prabu, JK Fang… - Journal of Biological …, 2004 - ASBMB
A transcription suppressor element (sequence–481 to–320) containing a G-rich motif
(designated GTG) and a newly identified CAT-rich motif (designated CATR) was previously
shown to modulate expression of the mouse cytochrome c oxidase Vb gene during
myogenesis. Here, we show that the GTG element is critical for transcription activation in
both undifferentiated and differentiated myocytes. Mutations of the CATR motif abolished
transcription repression in myoblasts while limiting transcription activation in differentiated …
(designated GTG) and a newly identified CAT-rich motif (designated CATR) was previously
shown to modulate expression of the mouse cytochrome c oxidase Vb gene during
myogenesis. Here, we show that the GTG element is critical for transcription activation in
both undifferentiated and differentiated myocytes. Mutations of the CATR motif abolished
transcription repression in myoblasts while limiting transcription activation in differentiated …