MYC, MAX, and small cell lung cancer
CM Rudin, JT Poirier - Cancer discovery, 2014 - AACR
Cancer discovery, 2014•AACR
In this issue of Cancer Discovery, Romero and colleagues identify somatic mutations and
deletions of MAX, and also define what seem to be mutually exclusive alterations in MYC
family members and other MYC-associated factors in small cell lung cancer. Taken together,
these data highlight the importance of MYC signaling in small cell lung cancer and suggest
possible avenues for therapeutic intervention. Cancer Discov; 4 (3); 273–4.© 2014 AACR.
See related article by Romero et al., p. 292
deletions of MAX, and also define what seem to be mutually exclusive alterations in MYC
family members and other MYC-associated factors in small cell lung cancer. Taken together,
these data highlight the importance of MYC signaling in small cell lung cancer and suggest
possible avenues for therapeutic intervention. Cancer Discov; 4 (3); 273–4.© 2014 AACR.
See related article by Romero et al., p. 292
Abstract
In this issue of Cancer Discovery, Romero and colleagues identify somatic mutations and deletions of MAX, and also define what seem to be mutually exclusive alterations in MYC family members and other MYC-associated factors in small cell lung cancer. Taken together, these data highlight the importance of MYC signaling in small cell lung cancer and suggest possible avenues for therapeutic intervention. Cancer Discov; 4(3); 273–4. ©2014 AACR.
See related article by Romero et al., p. 292
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