Surgical treatment of drug-resistant epilepsy due to mesial temporal sclerosis: etiology and significance

MA Falconer, DC Taylor - Archives of neurology, 1968 - jamanetwork.com
THERE is now general agreement 1-3 that in about 50% of institutionalized epileptic
patients who die of natural causes, an autopsy will disclose a lesion. This was first
demonstrated macroscopically in 1825, in 9 out of 18 cases, by Bouchet and Cazauvieilh, 1
who called it Ammon's horn sclerosis (synonyms—sclerosis of the cornu Ammonis and
hippocampal sclerosis). Its histopathology was subsequently described in 1880 by Sommer.
4 This lesion has also been called" incisural sclerosis" 5 and" pararhinal sclerosis". 6, 7 Both …