Regulatory T cells and inflammatory bowel disease

H Groux, F Powrie - Immunology today, 1999 - cell.com
H Groux, F Powrie
Immunology today, 1999cell.com
Recent studies have identified interleukin 10 as a differentiation factor for a novel subset of
immune suppressive regulatory T cells. Here, Hervé Groux and Fiona Powrie discuss the
role that these cells play in the regulation of immune responses to enteric antigens and
suggest that a deficiency in these cells might be involved in the pathogenesis of
inflammatory bowel disease.
Abstract
Recent studies have identified interleukin 10 as a differentiation factor for a novel subset of immune suppressive regulatory T cells. Here, Hervé Groux and Fiona Powrie discuss the role that these cells play in the regulation of immune responses to enteric antigens and suggest that a deficiency in these cells might be involved in the pathogenesis of inflammatory bowel disease.
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