Parasitological and immunological aspects of early Ascaris spp. infection in mice

PH Gazzinelli-Guimarães… - International journal for …, 2013 - Elsevier
Studies related to the immunobiological aspects of an Ascaris spp. infection are still scarce,
especially those that aim to elucidate the early events of the immune response. In this study,
we demonstrated a novel standardized method for early experimental Ascaris infection,
providing additional information about the infectivity of eggs embryonated in vitro as well as
the influence of host age on development of the infection. Finally, we characterised the
immunopathology of early infection, focusing on the tissue and systemic cytokine profiles …