Eosinophil extracellular trap cell death–derived DNA traps: Their presence in secretions and functional attributes
S Ueki, Y Konno, M Takeda, Y Moritoki… - Journal of Allergy and …, 2016 - Elsevier
Background Activated human eosinophils, as well as neutrophils, can release extracellular
chromatin to form DNA traps through cytolytic extracellular trap cell death (ETosis). Although
formations of neutrophil DNA traps are recognized in patients with various inflammatory
conditions, neither the presence of ETosis-derived eosinophil DNA traps in human allergic
diseases nor the characteristics of these DNA traps have been studied. Objective We
investigated the presence of ETosis-derived DNA traps in eosinophil-rich sinus and ear …
chromatin to form DNA traps through cytolytic extracellular trap cell death (ETosis). Although
formations of neutrophil DNA traps are recognized in patients with various inflammatory
conditions, neither the presence of ETosis-derived eosinophil DNA traps in human allergic
diseases nor the characteristics of these DNA traps have been studied. Objective We
investigated the presence of ETosis-derived DNA traps in eosinophil-rich sinus and ear …