Helminth parasite infections are associated with a battery of immunomodulatory
mechanisms that affect all facets of the host immune response to ensure their persistence
within the host. This broad-spectrum modulation of host immunity has intended and
unintended consequences, both advantageous and disadvantageous. Thus the host can
benefit from suppression of collateral damage during parasite infection and from reduced
allergic, autoimmune, and inflammatory reactions. However, helminth infection can also be …