Shall we call them “telomere-mediated”? Renaming the idiopathic after the cause is found

SJ Merck, M Armanios - European Respiratory Journal, 2016 - Eur Respiratory Soc
SJ Merck, M Armanios
European Respiratory Journal, 2016Eur Respiratory Soc
Short of lung scarring, the idiopathic interstitial pneumonias (IIPs) primarily share their poorly
understood aetiology. Attempts to identify features that refine the distinctions between IIP
diagnostic categories, based on pathologic and radiographic criteria, have led to recent
revisions in their evaluation [1, 2]. The consensus recommendation relies on
multidisciplinary assessment to clarify an IIP diagnosis [2]. However, there still remains a
relatively low concordance rate across groups of experienced clinicians [3, 4] and the …
Short of lung scarring, the idiopathic interstitial pneumonias (IIPs) primarily share their poorly understood aetiology. Attempts to identify features that refine the distinctions between IIP diagnostic categories, based on pathologic and radiographic criteria, have led to recent revisions in their evaluation [1, 2]. The consensus recommendation relies on multidisciplinary assessment to clarify an IIP diagnosis [2]. However, there still remains a relatively low concordance rate across groups of experienced clinicians [3, 4] and the heterogeneity of the clinical course within IIP subtypes poses a challenge to using these categories when making decisions at the bedside [2].
European Respiratory Society